Parkinsons Disease Model

Parkinson's is a progressive neurological condition. It is estimated that 6.3 million people have Parkinson's worldwide.

Some people with Parkinson's disease notice that as the disease progresses their vision loses sharpness or becomes blurred. Difficulties related to the eyes and vision often progress alongside other Parkinson's symptoms.

We are investigating the role of Parkinson's disease in the Visual System, using a drosophila model of the disease. Both human, and fly models of the disease show a loss of visual acuity, caused by underlying changes in the photoreceptors ability to deal with changing light contrast levels.

Here we demonstrate a model of this disease state, as a change in the photoreceptor response to changes in contrast. Press the Play button on the Control Bar to see the retina in action. You can Investigate each Neuron Trace by clicking on the individual photoreceptors on the right.

Photoreceptor Input

Photoreceptor Output

Natural Scene

Visual Field

Healthy Retina

Diseased Retina